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肝细胞癌组织学分类、分级及PCNA、Ki-67的表达 被引量：2

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摘要 肝细胞癌病理组织学分级、组织生长方式、细胞增殖活性对其治疗和预后有重要意义。在与细胞周期相关的核抗原的免疫组织化学研究中,多使用PCNA和Ki-67两种标记,来反映肝细胞癌组织细胞的增殖状态。PCNA和Ki-67的表达水平与肝癌细胞的分化、浸润、转移等生物学行为等密切相关。
作者 李玉亮 刘延军
机构地区 山东省医学影像学研究所 山东省陵县人民医院
出处 《国外医学（临床放射学分册）》 2002年第5期287-289,共3页
关键词 病理组织学 增殖细胞核抗原 肿瘤分化 肿瘤浸润 肿瘤转移 肝细胞癌
分类号 R735.7 [医药卫生—肿瘤]
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参考文献16

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同被引文献24

  • 1陈燕昌,林舜国,郑宇辉,梁建纲,许春森,韩晖,陈大良.乳腺癌Ki-67抗原和DNA倍体的相关性及临床意义[J].福建医科大学学报,2005,39(1):48-50. 被引量：15
  • 2赵华,绕慧兰,曾宗渊.诱导化疗对舌鳞癌肿瘤细胞增殖的影响[J].现代肿瘤医学,2005,13(3):371-373. 被引量：2
  • 3范志强,姜佑三,徐勇,张彤.PCNA、MMP9和E-cd在膀胱移行上皮癌中表达及意义[J].天津医药,2005,33(7):405-407. 被引量：5
  • 4李俊,江孝清,周绪红.p73和PCNA的表达与喉鳞状细胞癌的预后[J].临床耳鼻咽喉科杂志,2005,19(24):1121-1124. 被引量：9
  • 5Hall PA,Levison DA,Woods AL,et al.Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections:an index of cell proliferation with evidence of deregulated expression in some neoplasms[J].J Pathol,1990,162 (4):285-294.
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  • 8Zhang Z,Yamashita H,Toyama T,et al.Semi-quantitative immunohistochemical analysis of aromatase expression in ductal carcinoma in situ of the breast[J].Breast Cancer Res Treat,2002,74(1):47-53.
  • 9Ming DS,Hillhouse BJ,Guns ES,et al.Bioactive compounds from Rhodiola rosea (Crassulaceae)[J].Phytother Res,2005,19(9):740-743.
  • 10Majewska A,Hoser G,Furmanowa M,et al.Antiproliferative and antimitotic effect,S phase accumulation and induction of apoptosis and necrosis after treatment of extract from Rhodiola rosea rhizomes on HL-60 cells[J].J Ethnopharmacol,2006,103 (1):43-52.

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国外医学（临床放射学分册）
2002年 第5期

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