抗生素序贯治疗小儿肺炎疗效观察

Observation on Efficacy of Sequential Therapy of Antibiotic in Children with Pneumonia

目的 为了评价抗生素序贯治疗小儿肺炎的治疗效果。方法 病例为儿科门诊年龄 3个月～ 5岁、病程在 5天内 ,未使用抗生素的肺炎患儿 184例 ,按随机编号分别给予抗生素序贯治疗或全程静脉给药治疗。结果 共有 173例完成本试验。抗生素序贯治疗组治愈率为 82 .6% ,对照组为 90 .2 % ,χ2 =1.40 ,P =0 .2 4。两组治愈病例症状、体征消失天数 ,X线胸片阴转率作统计学分析P均 >0 .0 5。差别无显著意义。结论 抗生素序贯治疗小儿肺炎具有良好的效果。

Objective To evaluate the effect of sequential therapy of antibiotic in children with pneumonia.Method 184 children with pneumonia aged 3 months～5 years,fallen ill less than 5 days and never taken antibiotic were divided into two groups randomly:treatment group(treated with antibiotic seqentially) and control group(treated with intravenous injection in whole course).Results There were 173 cases completed the trial. In treatment group and control group,cure rates were 82.6% and 90.2%,respectively(χ 2=1.40, P =0.24).There were no significant differences between the two groups in the time of symptoms disappearance and the negative turnover rate of abnormal chest X ray test.Conclusion Sequential therapy of antibiotic is effective to children pneumonia.