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冠心病患者脂蛋白(a)水平与冠状动脉狭窄的关系 被引量：3

CORRELATION OF SERUM LIPOPROTEIN(A) WITH STENOSIS OF CORONARY IN PATIENTS WITH CORONARY ARTERY DISEASE
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摘要 目的 :探讨血清脂蛋白 (a) [Lp(a) ]与冠状动脉狭窄程度的关系。方法 :将 91例冠脉造影患者按狭窄程度分组 ,比较各组血清Lp(a) ,C反应蛋白及血脂指标等 ,进行统计学分析。结果 :血清Lp(a)水平在冠脉明显狭窄以及多支血管病变中显著升高 ,Lp(a)异常率在冠脉造影阴道与冠脉造影阳性患者中有明显差异。结论 :Lp(a)水平与冠脉状狭窄程度明确相关 ,在冠状动脉粥样斑块形成以及破裂过程中起着重要作用。 Objective:To demonstrate the correlation of serum Lipoprotein (a) to stenosis of coronary artery.Methods:We divided 91 patients with angiographic findings into 30 groups and analyzed their blood specimen for Lp(a) and C_reactive protein,etc.Results:There was a singnificant upward trend of Lp(a) levels compared with the degree and multiple vessels of coronary stenosis.The rate of abnormal Lp(a) in patients with severty coronary stenosis was higher than that in normal coronary artery.Conclusions:Serum Lp(a) levels correlated with the degree of coronary stenosis.The Lp(a) plays an important role in the forming and disruption of plague in coronary artery.
作者 刘松岩 马迪戈 孙世安
机构地区 武警新疆总队医院心内科
出处 《中国现代医学杂志》 CAS CSCD 2002年第13期43-44,共2页 China Journal of Modern Medicine
关键词 冠心病 动脉粥样硬化 冠状动脉狭窄 脂蛋白 CHG 冠脉造影 Atherosclerosis Coronary Artery Stenosis Lipoprotein(a)
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献5

  • 1[1]Dahlen GH, Lipoprootein ( a ) in cardiovascular disease [ J ].Atherosclerosis, 1994; 108:111
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同被引文献17

  • 1汪俊军,王素梅,强宏娟,张春妮,庄一义.血清脂蛋白(a)特异性循环免疫复合物的检测及临床应用[J].中华检验医学杂志,2004,27(6):355-358. 被引量：4
  • 2王西平,韦建瑞,郭晓碧.益欣康泰胶囊对冠心病心绞痛的疗效及其对血浆内皮素和一氧化氮水平的影响[J].中国医院药学杂志,2004,24(9):541-542. 被引量：12
  • 3Song Fangwen, Huang Shijie . Observed the dinical effects of yixinkangtai on middle-old age operation patient [M]. In: International medical experts academic sympositma, Academic europeerme de sciences naturelles Engelhardt - Ng verlag. Borm: Germany Combined Publication ,2002: 531.
  • 4TANIGUCHI H,MOMIYAMA Y,OHMORI R,et al.Associations of plasma C-reactive protein levels with the presence and extent of coronary stenosis in patients with stable coronary artery disease[J].Atherosclerosis,2005,178(1):173-177.
  • 5PERSSON GR,PETTERSSON T,OHLSSON O,et al.High-sensitivity serum C-reactive protein levels in subjects with or without myocardial infarction or periodontitis[J].J Clin Periodontol,2005,32(3):219-224.
  • 6ABOU DIWAN CH,OGHLAKIAN GO,et al.The role of high sensitivity C-reactive protein in coronary artery disease risk prediction:a review[J].J Med Liban,2004,52(1):39-47.
  • 7KULLER LH,TRACY RP,SHATEN J,et al.Relation of C-reactive protein and coronary heart disease in the MRFIT nested case control study[J].Am J Epidemiol,1996,144(6):537-547.
  • 8YAZIC1 M,DEMIRCAN S,DURNA K,et al.Lipoprotein(a) levels in patients with unstable angina and their relationship with atherothrombosis and myocardial damage[J].Int J Clin Pract,2005,59(2):150-155.
  • 9TSIMIKAS S,BRILAKIS ES,MILLER ER,et al.Oxidized phospholipids,Lp(a) lipoprotein,and coronary artery disease[J].N Engl J Med,2005,353(1):46-57.
  • 10SEED M,AYRES KL,HUMPHRIES SE,et al.Lipoorotein(a)as a predictor of myocardial infaction in middle-aged men[J].Am J Med,2001,110(1):22-27.

引证文献3

二级引证文献23

中国现代医学杂志
2002年 第13期

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