益气补肾活血法治疗儿童特发性血小板减少性紫癜及血小板聚集功能的变化

Idiopathic Thrombocytopenic Purpura in Children Treated with Replenishing Qi and Tonifying Kidney and the Changes of Thrombocyte Aggregative Function

应用益气补肾活血法为主治疗41例特发性血小板减少性紫癜,结果治愈及恢复率达73.3%,总有效率97.6%;治疗后血小板聚集功能恢复至正常。停药后随访疗效巩固。

Forty-one children with idiopathic thrombocytopenic purpura(ITP)were reported in this paper. Of all,36 with petechia and ecchymosis,28 with nasal hemorrhage,5 withhematochezia and 1 with subcutaneous hematoma.According to the TCM differentiation,24 and 17 of all belofiged to the type of impairment,of Yin(阴)due to blood-heat and both deficiencies of Qi and tonifying Kidney and its basic prescriptions were:dried Radix Rehmanniae,Radix Angelicae Sinensis,Radix Paeoniae Rubra, Radix Rubiae,Fructus Psoraleae,stir-frying Radix Astragali,Semen Cuscutae,Caulis Spatholob, Chinese Jujubae,Radix et Rhizoma Rhei.The average treating duration was 5.02 months.Results: 24 cases cured,6 recovered,10 improved,1 failed,with a total effective rate of 97.6%.22 of the cured were followed-up without recurrence in average 10.4 months after withdrawal.In 32 cases,the thrombocyte aggregative function was tested with ADP induction,meanwhile in 20 of 32 cases aggregation with adrenaline induction was tested.The results before and after treatment showed an evident difference,with low function before treatment and normal after treatment.It is concluded that the replenishing Qi and tonifying Kidney may have a better effect on both acute and chronic children ITP without recurrence after withdrawal.