运脾方药治疗小儿厌食症的临床与实验研究

Abstracts of Original Articles Clinical and Experimental Study on Treatment of Anorexy in Children with the Activating Spleen Prescription

治疗小儿厌食症488例,辨证中药(运脾、补运兼施两法)组疗效显著优于浓复 B 液对照组(P<0.001)。实验研究结果:运脾方药儿宝冲剂能提高患儿尿 D-木糖排泄率和头发锌、铁、钴、锶等8种元素含量,增加血 T 淋巴细胞比值和唾液 SIgA 含量,调节实验家兔异常肠蠕动,增进家兔离体十二指肠对氨基酸和葡萄糖的吸收。补运兼施方药健儿糖浆能提高患儿头发锌、铁、铜、锰等14种元素含量,增加血T淋巴细胞比值,提高实验小鼠的胸腺指数及脾指数,增进小鼠溶血素生成。提出运脾法为主治疗小儿厌食症的作用机理,主要在于增进食欲,促进机体对各种营养物质,包括必需微量元素的吸收和利用。

The treatment of 488 cases with anorexy in children showed that the curative effect of the group using Chinese medicines based on the differentiation of symptoms and signs by(1)activating the Spleen,(2)invigorating and activating the spleen was significantly higher than the control using concentrated vitamin B complex(P<0.001).The results of the experimental study were as follows: Erbao(儿宝)instant granules(the medicine for activating the Spleen)had the effect of raising the D-xylose excretion rate of urine;increasing the ratio of T-lymph cells in blood;raising the quality of 8 mineral elements in hair and the quality of SIgA in saliva;adjusting the abnormal peristalsis of the experimental rabbits and promoting the ability that duodenums which had been separated from rabbits had to absorb different amino acids and glucose.Jian'er(健儿)syrup(the medicine for invigorating and activating the Spleen)had the effect of raising the quality of 14 mineral elements in hair;increasing the ratio of T-lymph cells in blood;increasing the index of thymus and spleen in the experimental rats and stimulating them to produce hemolysin.The authors tend to think that the therapeutic principle of activating the Spleen can improve appetitc,help the body to absorb and utilize various nutrients which contain many kinds of essential trace elements.