小儿泻速停冲剂治疗小儿腹泻419例临床与实验研究

Clinical and Experimental Study on the Treatment of Children Diarrhea by Granule of Children-Diarrhea Fast-Stopping

小儿泻速停冲剂是由乌梅、山楂炭、地锦草等七味中药组成的经验方,治疗小儿腹泻419例,总有效率96.4%,治愈率90%,明显优于对照组(中药组葛连散及参苓白术散,西药组庆大霉素及吡哌酸);同时可明显缩短止泻的起效时间和治愈时间,并优于对照组。对急、慢性腹泻,病毒、细菌所致的感染性、非感染性腹泻及中焦湿热型、脾虚型腹泻均有良效。临床及动物实验证实该药无毒、副作用。其治疗腹泻的机理主要有(1)抑制病菌以消除病因;(2)调整及提高机体的免疫功能;(3)促进肠道消化及吸收功能的恢复;(4)抑制肠管运动。因此可对多型腹泻具有快速止泻的作用,符合世界卫生组织对防治腹泻新药的要求。

Granule of children-diarrhea fast-stopping is a proved recipe composed of seven medical herbs such as Poria cocos,haw charcoal,Euphorbia humifusa,etc.After more 20 years'clinical application of 419 cases,the total effective rate proved to be 96.4% and the cure rate 90%,much better than the control groups[TCM:Gelian San(葛连散)and Shenglingbaizhu San(参苓白术散);WM:gentamycin and PPA].It had the effect of fast-stopping diarrhea and shortening the recovery period.It also had excellent curative effect for acute and chronic.diarrhea,for noninfective and infective diarrhea with virus or germs,and for the diarrhea due to moist heat and Spleen weakness in TCM.Clinical tests and experiments showed that this medicine had no toxic or side effects.The diarrhea-cure mecha- nisms were(1)Inhibiting germs so as to eliminate pathogeny.(2)Adjusting and improving organism immunity function.(3)Accelerating the recovery of intestinal digestion and absorption functions.(4) Inhibiting intestinal movement.