1Maisonpierre PC, Suri C, Jones PF, et al. Angiopoietin-2, a natural Antagonist for Tie-2, That Disrupts in vivo Angiogenesis[J]. Science,1997,227:55-60.
2Procopio WN,pelavin PI, Lee MF, et al. Angiopoietin-l and -2 Coiledcoiled Domains Mediate Distinct Homo-oligo merization Patterns, but Fibrinogen-like Domains Mediate ligand Activity[J]. J Biol Chem,2000,274(42): 30196 - 30201.
3Kim IJ, Kim JH, Ryu YS, et al. Characterization and Expression of a Novel Alternatively Spliced Human Angiopoietin-2 [J]. J Biol Chem,2000,275(24): 18550 - 18556.
4Suri C, Jones PF, Patan S, et al. Requisite Role of Angiopoietin-1, a Ligand for the Tie-2 Receptor during Embryonic Angiogenesis[J]. Cell,1996,87:1171 - 1180.
5Chae JK, Kim I,Lim ST, et al. Coadminstration of angiopoietin-1 and vascular endothelial growth factor enhances collateral vascularization[J].Artedoscler Thromb Vasc Biol, 2000,20(12) :2573-2578.
6Teichert KK, Maisonpierre PC,Jones N, et al. Biological action of angiopoietin-2 in a fibrin matrix model of angiogenesis is accociated with activation of tie2[J]. Cardiorasc Res,2001,49(3) :659 - 670.
7Suri C, Mcclain J,Thurston G, et al. Increased Vascularization in Mice Overexpressing Angiopoietin-1 [J]. Science, 1998,282(16) :468 - 471.
8Kampfer H,Pfeischifter J,FrankS, et al. Expression regulation of angiopoietin-1 and -2 and the tie-land -2 receptor tyrosine kinases during cutaneoue wound healing: a comparative study of normal and impaired repaire[J]. Lab Invest,2001,81(3) :361 - 373.
9Hackett SF, Ozaki H,Strauss RW, et al. Angiopoietin-2 expression in the retina: upregulate during physiologic and pathologic neovasularization [J]. J Cell Physiol,2000,184(3) :275 - 284.
10Otani A,Takagi H,Oh H, et al. Expression of angiopoietins and tie2 in human choroidal neovascular membranes[J]. Invest Ophthalmol Vis Sci,1999,40(9): 1912 - 1920.
5Maisonpierre PC, Suri C, Jone PF, et al. Angiopoietin-2, a natural an-tagonist for Tie-2 that disrupts in vivo angiogenesis[J]. Science, 1997,277 (5322) : 55-60.
6Hayes AJ, Huang WQ, Yu J, et al. Expression and function of angiopoi-etin-1 in breast cancer[J]. Br J Cancer,2000,83(9) : 1154-1160.
7Etoh T, lnoue H, Tanaka SJ, et al. Angiopoietin-2 is related to tumor angiogenesis in gastric carcinoma possible in vivo regulation via induc-tion of proteases[J]. Cancer Res, 2001,61 (1) :2145-2153.
8Ahmad SA, Liu WB, Septg YD, et al. The effects of angiopoietin-1 and-2 on tumor growth and angiogenesis in human colon cancer[J]. Canaer Res, 2001,61 (15) : 1255-1259.
9Wurmbacl JH,Hammerer P, Sevinc S, et al. The expression of anglo-genesis and their receptor Tie-2 in human prostate carcinoma[J]. Anti-cancer Res,2000,20(6D) :5217-5220.
10O' Reilly MS, Holmgren L, Shing Y, et al. Angiostatin : a noval angio-genesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma[J]. Cell, 1994,79(2) :315-328.