咳喘平汤剂治疗慢性支气管炎临床及实验研究

Clinical Observation and Experimental Researehon Chronic Bronchitis Treated with Ke Chuan Ping(咳喘平)Decoction

运用自拟方咳喘平治疗急发期与慢迁期慢性支气管炎31例的临床与实验研究,并以古方清金化痰汤作为对照(31例)。结果:观察组控显率为67.74%,总有效率为93.55%;对照组控显率为41.94%,总有效率有74.19%,两组比较有显著性差异,P<0.05。动物实验结果提示,咳喘平具有较强的祛痰、镇咳、平喘和抑菌作用,与对照方比较差异非常显著,P<0.01。临床与实验的资料均证实,本方不失为治疗慢性支气管炎有效方剂。

This paper presents the results of clinical,observation and experimental research of Ke Chuan Ping(KCP)in treating 31 cases of chronic bronchitis compared with that of traditional prescription Qing Jin Hua Tan(清金化痰)decoction(QJHT)in other 31 patients with the same conditions random- ized as control.The total effective rate of KCP group was93.55%including 67.74% of basically cured and markedly effective cases.The total effectlve rate of QJHT group was 74.19% including 41.94% basically cured and markedly effective cases.There were significant differences between them(P< 0.05).According to laboratory observation KCP had the ability to dilute sputum viscosity,promote pulmonary ventilation function,decrease WBC and raise PO_2.Animal experimental research sug- gested that KCP had the effects on reducing sputum,relieving cough,modifying stridor and inhibiting bacteria.It was proved that KCP is a highly effective recipe for patients with chronic bronchitis.It was also shown that clearing away heat and dispersing phlegm therapy is an important measure for chronic bronchitis with Biao Zheng(标证).