壶腹周围憩室和胆道结石的关系探讨

Relationship of periampullary diverticula to biliary tract stone

目的 探讨壶腹周围憩室（PAD）与胆道结石的关系以及内镜诊断PAD的应用价值。方法选择284例经内窥镜逆行胰胆管造影（ERCP）检查确诊合并有PAD的患者（PAD组）与同期经ERCP检查无PAD的患者（对照组）作为对照研究。胆道疾病根据病史、体征、给合实验室检查上超、CT以及ERCP等确诊。结果PAD组合并胆囊结石、胆总管结石、胆总管下端括约肌功能不良患者明显多于对照组,尤以胆总管结石增多为主（P<0.01）。结论PAD与胆道结石有着密切关系,PAD可能是胆道结石发生或复发的一个重要因素。

Objective To study the relationship of periampullary diverticula (PAD) to biliary stone and the apply value of endoscope diagnosis for periampullary diverticula. Methods Selecting to 284 cases with PAD (PAD group) were applied and detected by endoscopic retrograde cholangiopancreatography (ERCP), as the same time, 284 cases (contrast group) without PAD were detected ERCP and performed on a contrastive study. According to History, signs, laboratory findings, BUS, or CT and ERCP, the biliary tract stone were detected. Results The PAD group are present in a significantly greater number of patients with cholelithiasis olecystolithiasis, choledocholith, choledochus sphincteric dysfunction than without the condition, the number of choledocholith patients is outstandingly greater with PAD than without PAD in the PAD group ( P < 0. 01). Conclusions There is a close relationship between PAD and biliary tract stone. PAD may be a kind of important element which can lead to the occurrence or recurrence of biliary tract stone.