复方黄瓜藤片治疗高血压病的临床及实验研究

Clinical and Experimental Study of Tablet Cucumber Vine Compound in Treating Essential Hypertension

用复方黄瓜藤片治疗高血压病241例,缓解症状显效率为63.1%,总有效率为81.7%;降低血压显效率为52.7%,总有效率90.9%。实验证明,该复方具有降压,利尿、增加冠脉流量和增强心肌收缩力作用,毒副作用很小,是临床治疗高血压病的一种安全有效的药物。

389 patients with essential hypertension were divided into two groups randomly.241 patients were treated by tablet of cucumber vine compound and 148 patients by tablet of hypotension compound as control.The symptomatic marked improvement and total effective rate were 63.1% and 81.7% in the treated group and 39.2% and 67.0%(P<0.01)in the control group respectively.The marked effective rate in decrease of blood pressure and total effective rate were 52.7%,90.9% and 58.1%,92.6%(P>0.05)respectively.Experiments with animals showed that tablet cucumber vine compound possessed persistently decreasing effect on the blood pressure and marked effect on increasing coronary blood flow and hnproving myocardial contraction.Clinical observation and toxicological test proved that tablet cucumber vine compound had no toxicity and had few side effects and that it was an effective,safe medicine for essential hypertension.