107例闭塞性动脉硬化患者体外血栓形成观察

Observation on Thrombosis Test in vitro of 107 Cases with Arteriosclerosis Obliterans

对107例闭塞性动脉硬化患者和36名健康人测定体外血栓各值,并结合临床分期分级及中医辨证分型,中西医结合治疗等进行观察、分析。结果:(1)患者组体外血栓各值均显著地高于健康人(P<0.001)。(2)临床分期、分级、中医分型不同,其体外血栓各相应值之间存在明显差异(P<0.05～0.001)。(3)中西医结合治疗前后体外血栓各值之间存在非常显著的差异(P<0.001)。表明体外血栓结果可反映临床病情变化,可作为本病临床分期分级、中医分型和判定疗效的客观指标。

Thrombosis test in vitro of 107 cases with arteriosclerosis obliterans were measured and controlled by 36 normal persons.Of 107 cases,13 cases belonged to ischemic phase,47 cases nutritional disturbance phase,47 necrosis (24 cases were first degree,9 cases second degree,14 third degree).Types distribution were:simple blood stasis 65 cases,blood and damp stasis 34,and 8 others. 46 patients were treated systematicly by TCM-WM.The result proved that the indexes of thrombo- sis test in vitro of patients were much.higher than that of normal persons (P<0.001).The relevant indexes were different in varied periods,degrees and types (P<0.05～0.01) and between before and after treatment (P<0.001).Of treated 46 cases,total effective rate was 86.96%,amputation rate was 13.04%.Formation of thrombus in vitro lowered 88.03%.The authors suggested that measurement of thrombosis test might be a accurate way to reflect the course of the disease and a basis for treatment and differentiation of symptoms.