旋毛虫成虫可溶性抗原免疫小鼠T淋巴细胞亚群的动态变化

Dynamic changes of T lymphocytes subsets in Trichinella spiralisAWAg immune mice

目的 观察旋毛虫成虫可溶性抗原免疫小鼠T淋巴细胞亚群的动态变化。方法采用流式细胞术分别检测旋毛虫感染后 7、14、2 1、2 8、35天小鼠外周血CD+ 4 、CD+ 8T淋巴细胞的百分率。结果 免疫小鼠CD+ 4 、CD+ 8细胞增加 ,CD+ 4 /CD+ 8细胞比值与正常组比较无明显差异。

Objective To observe dynamic changes of T lymphocyte subsets in Trichinella spiralis adult worm soluble antigens (AWAg) immune mice Methods The percentage of CD + 4 and CD + 8 T cells were examined by flow cyteometry on 7,14,21,28,35 days after mice infected with Trichinella spiralis respectively Results CD + 4 and CD + 8 T cells of immune mice increased,the ratio of CD + 4/CD + 8 cells was no difference comparing with normal mice Conclusions The immune function of AWAg immune mice was no inhibited