龙胆解毒汤治疗亚急性甲状腺炎疗效观察

Evaluation of Long Dan Jie Du Decoction on the Treatment of Subacute Thyroiditis

目的观察龙胆解毒汤治疗亚急性甲状腺炎的疗效。方法将亚急性甲状腺炎病人７２例分为两组：强的松组３２例，给予强的松片每日３０４０ｍｇ，晨１次口服；龙胆解毒汤组４０例，给予龙胆解毒汤一剂煎，每日２次口服，均二周为１疗程。观察１６个疗程后随访３个月。结果强的松组２周治愈率为３４３８％，好转率为３１２５％，总有效率６５６３％；龙胆解毒汤组２周治愈率为７２５％，好转率为２２５０％，总有效率９５００％。两组相比，Ｐ＜０．０１，差异有非常显著性。随访３个月，强的松组并发症发生率占６５６３％，毒副作用发生率占７８１３％；龙胆解毒汤组并发症发生率占７５０％，无毒副作用发生。两组相比，Ｐ＜０．０１，差异也有非常显著性。结论龙胆解毒汤治疗亚急性甲状腺炎不仅疗效好，疗程短，而且并发症和毒副作用也远较强的松少得多。

Objective To observe the effects of Long Dan Du decoction (LDJDD) on the treatment of subacute thyroiditis (ST).Methods Seventy two patients with ST hospitalized from Jan,1991 to Dec,1996 were divided into two groups voluntarily.1)32 patients in Prednisonum control group,with predinisonum tablets 30￣40 mg/day,one time in every morning.2)40 patients in LDJDD treatment group,with LDJDD twice a day.Two weeks as one course of treatment in both groups.After two weeks,the therapeutical effects were evaluated.Those who were not cured could go on the treatments for 2￣6 courses and be followed up for 3 months,the complications and the adverse effects were observed.[WT5”HZ]Results In predinisonum control group,the cure rate in two weeks was 34.38%,the improvement rate was 31.25%,the total effective rate was 65.63%.In LDJDD treatment group,the cure rate in two weeks was 72.50%,the improvement rate was 22.50%,the total effective rate was 95.00%.After followed up for 3 months,the incidence rate of complication in prednisonum group was 65.63%,while in LDJDD treatment group it was 7.50%.The incidence rate of adverse effects in predinisonum group was 78.13%,while no adverse effect was found in LDJDD group.Conclusion It was showed that LDJDD not only has better curative effect and shorter courses than predinisonum on the treatment of ST,but also has fewercomplication and adverse effects.