摘要
Hereditary haemochromatosis (HH) is a common autosomal recessive systemic iron overload disorder in which CNS manifestations, particularly movement disorders, have been reported. We report a 63 year old woman with familial HH with a four year history of progressive gait disturbance, chorea, and mild cervical and laryngeal dystonia. Her movement disorder was thought to be related to the haemochromatosis. On further investigation, analysis for the Huntington’ s disease expansion was positive. A review of the seven published cases of movement disorders associated with HH as well as data concerning brain iron deposition in this condition leads us to debate the causal link between movement disorders and HH. We suggest that ovement disorders are rare in association with HH, and that such patients should be thoroughly investigated for another cause for their movement diorder.
Hereditary haemochromatosis (HH) is a common autosomal recessive systemic iron overload disorder in which CNS manifestations, particularly movement disorders, have been reported. We report a 63 year old woman with familial HH with a four year history of progressive gait disturbance, chorea, and mild cervical and laryngeal dystonia. Her movement disorder was thought to be related to the haemochromatosis. On further investigation, analysis for the Huntington’ s disease expansion was positive. A review of the seven published cases of movement disorders associated with HH as well as data concerning brain iron deposition in this condition leads us to debate the causal link between movement disorders and HH. We suggest that ovement disorders are rare in association with HH, and that such patients should be thoroughly investigated for another cause for their movement diorder.
出处
《世界核心医学期刊文摘（神经病学分册）》
2005年第1期12-13,共2页
Digest of the World Core Medical Journals:Clinical Neurology
