摘要
The distinction between chronic demyelinating polyneuropathies associated wit h IgM paraproteinemia and anti-myelin-associated glycoprotein (MAG) antibodi es (MAG- PN) and chronic inflammatory demyelinating polyneuropathies (CIDPs) r elies on the anti-MAG antibodies assay. The aim of the study was to identify c linical and electrophysiological features suggesting a diagnosis of MAG-PN. Fo urteen patients with MAG-PN and 35 with CIDP were included, and a discriminant analysis was performed to identify the clinical and electrophysiological featur es suggestive of MAG-PN. Pure sensory clinical phenotype, low median and ulnar terminal latency index, and absence of M responses in the lower limbs were sign ificantly associated with the diagnosis of MAG-PN, and indicate a moderate to large increase in probability of this diagnosis in patients with chronic dysimmu ne demyelinating polyneuropathies.
The distinction between chronic demyelinating polyneuropathies associated wit h IgM paraproteinemia and anti-myelin-associated glycoprotein (MAG) antibodi es (MAG- PN) and chronic inflammatory demyelinating polyneuropathies (CIDPs) r elies on the anti-MAG antibodies assay. The aim of the study was to identify c linical and electrophysiological features suggesting a diagnosis of MAG-PN. Fo urteen patients with MAG-PN and 35 with CIDP were included, and a discriminant analysis was performed to identify the clinical and electrophysiological featur es suggestive of MAG-PN. Pure sensory clinical phenotype, low median and ulnar terminal latency index, and absence of M responses in the lower limbs were sign ificantly associated with the diagnosis of MAG-PN, and indicate a moderate to large increase in probability of this diagnosis in patients with chronic dysimmu ne demyelinating polyneuropathies.
出处
《世界核心医学期刊文摘（神经病学分册）》
2005年第5期24-25,共2页
Digest of the World Core Medical Journals:Clinical Neurology
