摘要
Medical records and follow-up data were reviewed in 297 genetically proven myotonic dystrophy type 2 (DM2) patients. Patients were selected by the criteria of cardiac sudden death before age 45. Sudden death occurred in four patients, three of whom were cardiological asymptomatic, and one with a history of heart f ailure. Cardiac histopathology showed dilated cardiomyopathy in all, and conduct ion system fibrosis in two patients. Pathogenetic CCUG ribonuclear inclusions we re demonstrable in cardiomyocytes.
Medical records and follow-up data were reviewed in 297 genetically proven myotonic dystrophy type 2 (DM2) patients. Patients were selected by the criteria of cardiac sudden death before age 45. Sudden death occurred in four patients, three of whom were cardiological asymptomatic, and one with a history of heart f ailure. Cardiac histopathology showed dilated cardiomyopathy in all, and conduct ion system fibrosis in two patients. Pathogenetic CCUG ribonuclear inclusions we re demonstrable in cardiomyocytes.
出处
《世界核心医学期刊文摘（神经病学分册）》
2005年第5期45-45,共1页
Digest of the World Core Medical Journals:Clinical Neurology
