非破裂的颅内动脉瘤患者术前和术后的认知功能

Cognitive function before and after surgery in patients with unruptured intracranial aneurysm

Background and Purpose - This prospective study investigated whether surgery for unruptured intracranial aneurysms (UIAs)- affects cognitive function and cerebral blood flow (CBF). Methods - Cognitive tests using the Wechsler Adult Intelligence Scale- Revised, Wechsler Memory Scale, Rey- Osterrieth Complex Figure test, and CBF measurements using single- photon emission computed tomography were performed before and after surgery for UIAs in 44 patients ≤ 70 years of age. Results - Group- rate analysis showed the verbal intelligence quotient (IQ), performance IQ, full- scale IQ, and recall trial scores of the Rey- Osterrieth Complex Figure test all increased significantly after surgery, whereas the Wechsler Memory Scale and copy trial scores of the Rey- Osterrieth Complex Figure test were not significantly different. Event- rate analysis demonstrated that no patient showed impaired cognition. There was no significant difference between CBF before and after surgery. Conclusions - Surgical repair for UIAs does not impair cognition or CBF in patients without postoperative restrictions in lifestyle.