摘要
Objective: To develop a quantitative method of assessing cognitive anosognosia in six cognitive and two noncognitive domains.Methods: Control (n =32) and prob able Alzheimer disease(pAD) (n = 14) subjects self-estimated memory, attention, generative behavior, naming, visuospatial skill, limb praxis, mood,and uncorrec ted vision, both before and after these abilities were assessed. Based on this e stimate and their performance the authors calculated an anosognosia ratio (AR) b y dividing the difference between estimated and actual performance by an estimat ed and actual performance sum. With perfect awareness,AR = 0. Overestimating abi lities would yield a positive AR (≤1); underestimation would yield a negative A R (≥-1). Results: Relative to controls, pAD subjects demonstrated anosognosia. Pre-testing (off-line), pAD subjects overestimated their visuospatial skill; p ost-testing (on-line), pAD subjects overestimated their memory. Control subjec ts also made selfrating errors, underestimating their attention pre-testing and overestimating limb praxis and vision post-testing. Conclusions:This anosognos ia assessment method may allow more detailed examination of distorted self-awar eness. These results suggest that screening for anosognosia in probable Alzheime r disease (pAD) should include self-estimates of visuospatial function, and tha t, in pAD, it may be useful to assess anosognosia for amnesia both before and af ter memory testing.
Objective: To develop a quantitative method of assessing cognitive anosognosia in six cognitive and two noncognitive domains.Methods: Control (n =32) and prob able Alzheimer disease(pAD) (n = 14) subjects self-estimated memory, attention, generative behavior, naming, visuospatial skill, limb praxis, mood,and uncorrec ted vision, both before and after these abilities were assessed. Based on this e stimate and their performance the authors calculated an anosognosia ratio (AR) b y dividing the difference between estimated and actual performance by an estimat ed and actual performance sum. With perfect awareness,AR = 0. Overestimating abi lities would yield a positive AR (≤1); underestimation would yield a negative A R (≥-1). Results: Relative to controls, pAD subjects demonstrated anosognosia. Pre-testing (off-line), pAD subjects overestimated their visuospatial skill; p ost-testing (on-line), pAD subjects overestimated their memory. Control subjec ts also made selfrating errors, underestimating their attention pre-testing and overestimating limb praxis and vision post-testing. Conclusions:This anosognos ia assessment method may allow more detailed examination of distorted self-awar eness. These results suggest that screening for anosognosia in probable Alzheime r disease (pAD) should include self-estimates of visuospatial function, and tha t, in pAD, it may be useful to assess anosognosia for amnesia both before and af ter memory testing.
出处
《世界核心医学期刊文摘（神经病学分册）》
2005年第7期50-50,共1页
Digest of the World Core Medical Journals:Clinical Neurology
