摘要
Based on the hypothesis that mitochondrial myopathy, encephalopathy,lactic acidosis, and strokelike episodes (MELAS) are caused by impaired vasodilation in an intracerebral artery, the authors evaluated the effe cts of administering L-arginine, a nitricoxide precursor. Patients were adminis tered L-arginine intravenously at the acute phase or orally at the interictal p hase. L-Arginine infusions significantly improved all strokelike symptoms, sugg esting that oral administration within 30 minutes of a stroke significantly decr eased frequency and severity of strokelike episodes.
Based on the hypothesis that mitochondrial myopathy, encephalopathy,lactic acidosis, and strokelike episodes (MELAS) are caused by impaired vasodilation in an intracerebral artery, the authors evaluated the effe cts of administering L-arginine, a nitricoxide precursor. Patients were adminis tered L-arginine intravenously at the acute phase or orally at the interictal p hase. L-Arginine infusions significantly improved all strokelike symptoms, sugg esting that oral administration within 30 minutes of a stroke significantly decr eased frequency and severity of strokelike episodes.
出处
《世界核心医学期刊文摘（神经病学分册）》
2005年第7期50-51,共2页
Digest of the World Core Medical Journals:Clinical Neurology
