期刊文献+

环孢菌素引起的中毒性神经肌病(法国)

Cyclosporin-induced toxic neuromyopathy (Fren)
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摘要 Introduction. Cyclosporine is an immunosuppressive treatment whose side effect s limit its usefulness. Among neurological side effects, neuropathies or myopath ies have been reported, specially inpatients given combinations of cyclosporine with co-enzyme A reductase inhibitors. Case report. We report here the case of a 67-year-old woman who developed few months after a kidney graft sensorimotor disorders which progressed rapidly. Since all etiologies of such a disorder wer e ruled out,the hypothesis of toxicity exclusively induced by cyclosporine was s uggested and confirmed by the improvement observed after its withdrawal. Conclus ion. This observation highlights the fact that cyclosporine may induce neuromyop athies even when given alone at the therapeutic dosage. Introduction. Cyclosporine is an immunosuppressive treatment whose side effect s limit its usefulness. Among neurological side effects, neuropathies or myopath ies have been reported, specially inpatients given combinations of cyclosporine with co-enzyme A reductase inhibitors. Case report. We report here the case of a 67-year-old woman who developed few months after a kidney graft sensorimotor disorders which progressed rapidly. Since all etiologies of such a disorder wer e ruled out,the hypothesis of toxicity exclusively induced by cyclosporine was s uggested and confirmed by the improvement observed after its withdrawal. Conclus ion. This observation highlights the fact that cyclosporine may induce neuromyop athies even when given alone at the therapeutic dosage.
机构地区 Clinique Neurologique
出处 《世界核心医学期刊文摘(神经病学分册)》 2005年第8期8-9,共2页 Digest of the World Core Medical Journals:Clinical Neurology
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