摘要
Patients with muscular dystrophy may be prone to nutrient deficiency due to mo bility limitations or oropharyngeal weakness. Patients with myotonic muscular dy strophy (DM1) may be particularly prone to nutritional deficiencies from associa ted dysmotility of the entire gastrointestinal tract. We prospectively evaluated nutritional intake, body composition, and muscle strength in adult patients wit h DM1 (n=29) and other muscular dystrophies (n=22) on two occasions separated by ～6 months. Handgrip was significantly lower and knee extension higher for DM1 compared to other dystrophies, with no between-group differences in nutritional intakes. Many patients in both groups demonstrated inadequate nutrient intake o f protein, energy, vitamins (water and fat soluble), and minerals (calcium and m agnesium). Significant correlations were found between measures of strength and certain individual nutrients (e.g., copper and water-soluble vitamins). These d ata indicate that a substantial number of adults with muscular dystrophy do not meet current dietary intake recommendations. The potential clinical implications of these findings are discussed.
Patients with muscular dystrophy may be prone to nutrient deficiency due to mo bility limitations or oropharyngeal weakness. Patients with myotonic muscular dy strophy (DM1) may be particularly prone to nutritional deficiencies from associa ted dysmotility of the entire gastrointestinal tract. We prospectively evaluated nutritional intake, body composition, and muscle strength in adult patients wit h DM1 (n=29) and other muscular dystrophies (n=22) on two occasions separated by ～6 months. Handgrip was significantly lower and knee extension higher for DM1 compared to other dystrophies, with no between-group differences in nutritional intakes. Many patients in both groups demonstrated inadequate nutrient intake o f protein, energy, vitamins (water and fat soluble), and minerals (calcium and m agnesium). Significant correlations were found between measures of strength and certain individual nutrients (e.g., copper and water-soluble vitamins). These d ata indicate that a substantial number of adults with muscular dystrophy do not meet current dietary intake recommendations. The potential clinical implications of these findings are discussed.
出处
《世界核心医学期刊文摘（神经病学分册）》
2005年第9期43-43,共1页
Digest of the World Core Medical Journals:Clinical Neurology
