摘要
To report the birth of a normal healthy baby after a frozen ET (FET) with blastocysts that were frozen and thawed twice. Case report. Private infertility practice. A 26- year- old female who presented with male factor infertility and polycystic ovarian disease. One cycle of IVF- ETand FET no. 1 followed by the refreezing of blastocysts and FET no. 2. Clinical pregnancy and live birth. Thirty- six months after a successful IVF- ET cycle, FET no. 1 was performed with eight frozen blastocysts that were thawed. One blastocyst was transferred to the uterus and four were refrozen. The first FET resulted in a singleton pregnancy that ended in a spontaneous abortion after 7 weeks’ gestation. Six months later, FET no. 2 was performed. All four refrozen blastocysts were thawed and transferred to the uterus. The second FET resulted in a singleton pregnancy and the birth of a normal healthy baby (male) weighing 3,005 g after 38 weeks’ gestation. Human blastocysts can be refrozen/thawed and produce a normal healthy baby after anFET.Further studies will be required to determine survival, implantation, and live birth rates with refrozen/thawed human blastocysts.
To report the birth of a normal healthy baby after a frozen ET (FET) with blastocysts that were frozen and thawed twice. Case report. Private infertility practice. A 26- year- old female who presented with male factor infertility and polycystic ovarian disease. One cycle of IVF- ETand FET no. 1 followed by the refreezing of blastocysts and FET no. 2. Clinical pregnancy and live birth. Thirty- six months after a successful IVF- ET cycle, FET no. 1 was performed with eight frozen blastocysts that were thawed. One blastocyst was transferred to the uterus and four were refrozen. The first FET resulted in a singleton pregnancy that ended in a spontaneous abortion after 7 weeks’ gestation. Six months later, FET no. 2 was performed. All four refrozen blastocysts were thawed and transferred to the uterus. The second FET resulted in a singleton pregnancy and the birth of a normal healthy baby (male) weighing 3,005 g after 38 weeks’ gestation. Human blastocysts can be refrozen/thawed and produce a normal healthy baby after anFET.Further studies will be required to determine survival, implantation, and live birth rates with refrozen/thawed human blastocysts.
