摘要
Introduction. Familial dyskeratotic comedones is a rare affection of autosomal transmission and characterized by pseudo-comedone papules predominantly on the limbs. We report a new familial case characterized by its clinical and histolog ical profile. Case report. A 6 year-old boy presented with a papular, pseudo-c omedone eruption that had appeared shortly afterbirthandhadprogressivelyextended symmetricallytoboth legs. The child’s father complained of a similar eruption s ince childhood. Histological examination of the papules revealed a pseudo-folli cular invagination, obstructed by keratin and associated with areas of focal dys keratosis. Treatment with local retinoids was ineffective. Discussion. Since it is often asymptomatic, the prevalence of dyskeratosis comedones is probably unde restimated. A review of the literature on the preceding observations is presente d. The dermatites that would represent differential diagnoses because of the pre sence of comedone-like lesions and/or histological dyskeratosis are discussed.
Introduction. Familial dyskeratotic comedones is a rare affection of autosomal transmission and characterized by pseudo-comedone papules predominantly on the limbs. We report a new familial case characterized by its clinical and histolog ical profile. Case report. A 6 year-old boy presented with a papular, pseudo-c omedone eruption that had appeared shortly afterbirthandhadprogressivelyextended symmetricallytoboth legs. The child's father complained of a similar eruption s ince childhood. Histological examination of the papules revealed a pseudo-folli cular invagination, obstructed by keratin and associated with areas of focal dys keratosis. Treatment with local retinoids was ineffective. Discussion. Since it is often asymptomatic, the prevalence of dyskeratosis comedones is probably unde restimated. A review of the literature on the preceding observations is presente d. The dermatites that would represent differential diagnoses because of the pre sence of comedone-like lesions and/or histological dyskeratosis are discussed.
