摘要
We report a case of a 7- year- old girl with hyperimmunoglobulin- E syndrome presenting with widespread oral papillomas which were tested for human papilloma virus DNA and had shown to be at high/intermediate risk group formalignancy. She had elevated levels of IgE, recurrent sinopulmonary infections, atopic- like dermatitis, peripheral eosinophilia and defective neutrophil chemotaxis. Interferon alfa 2b therapy and chemoprophylaxis with sulfamethoxazole- trimethoprim was given. Although the papillomas partially improved with the treatment, sinopulmonary infections continue to occur.
We report a case of a 7- year- old girl with hyperimmunoglobulin- E syndrome presenting with widespread oral papillomas which were tested for human papilloma virus DNA and had shown to be at high/intermediate risk group formalignancy. She had elevated levels of IgE, recurrent sinopulmonary infections, atopic- like dermatitis, peripheral eosinophilia and defective neutrophil chemotaxis. Interferon alfa 2b therapy and chemoprophylaxis with sulfamethoxazole- trimethoprim was given. Although the papillomas partially improved with the treatment, sinopulmonary infections continue to occur.
