摘要
横纹肌肉瘤是儿童期最常见的软组织肉瘤。在婴儿期,葡萄状变异体从阴道或者膀胱处开始生长,但很少是从子宫颈处生长。治疗方法有从肿瘤的局部切除到根治性子宫切除并辅以药物治疗或者放射治疗。在子宫颈轻微浸润的病例中,微创的局部切除并辅以化疗的存活率相当高,而且不影响到膀胱、直肠、阴道和卵巢的功能。在这里,笔者将介绍30年以来的文献和1例5岁患有葡萄状子宫颈肉瘤女孩的病例报道。结论:根据文献以及笔者的观察,推荐对未成年人应该选择外科手术并辅以化疗的治疗方法来治疗Ⅰ期子宫颈横纹肌肉瘤。
Rhabdomyosarcomas are the most common soft tissue sarcomas in childhood. The botryoid variant arises in infancy from the vagina or urinary bladder and extremely rarely from the uterine cervix. Treatment regimes range from local excision of the tumour to radical hysterectomy with adjuvant multidrug therapy and/or radiotherapy. In cases of minimal cervical invasion, the less invasive local excision in combination with adjuvant chemotherapy has resulted in excellent survival rates with complete functional preservation of the bladder, rectum, vagina, and ovaries. We present here a 30 - year literature review and a case report of a cervical sarcoma botryoides in a 5 - yearold girl. Conclusion: Based on the literature review and our own observation, we recommend minor surgical approaches in combination with chemotherapy as the treatment of choice for early stage I cervical rhabdomyosarcoma.
