摘要
前瞻性地研究了严重细支气管炎插管患儿二十烷类物质的水平,并且将其与没有感染的选择性插管的婴儿进行比较。与对照比较,患细支气管炎的婴儿气管内(ET)吸出物中的白三烯E4(LTE4)、白三烯B4(LTB4) 和前列腺素E2(PGE2)水平均显著增高(P【0.01),尿中LTE4水平也增高(P【0.001)。笔者得出结论,细支气管炎患儿气管内吸出物和尿液中的二十烷类物质均增加。
We prospectively studied the levels of eicosanoids in intu-bated patients with severe bronchiolitis and compared them to electively intubated non-infected infants. LeukotrieneE4 (LTE4), leukotrieneB4 (LTB4), and prostaglandinE2 (PGE2) levels were significantly increased (P < . 01) from endotracheal (ET) aspirates of infants with bronchi-olitis compared with controls, as were urinary LTE4 levels (P < . 001) . We conclude that eicosanoids are increased in the tracheal aspirates and urine of children with bron-chiolitis.
