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致命水痘与选择性自然杀伤细胞缺陷有关

Fatal varicella associated with selective natural killer cell deficiency
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摘要 A 2- year- old girl with recurrent severe varicella infections had a fatal outcome. Studies of cellular and humoral immunity were normal. No natural killer (NK) cells were detected, and NK activity was markedly decreased. The interleuk in (IL)15/IL15R signaling pathway was intact. This case emphasizes the role of N K cells in controlling herpes viral infection. A 2- year- old girl with recurrent severe varicella infections had a fatal outcome. Studies of cellular and humoral immunity were normal. No natural killer (NK) cells were detected, and NK activity was markedly decreased. The interleuk in (IL)15/IL15R signaling pathway was intact. This case emphasizes the role of N K cells in controlling herpes viral infection.
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