机械信号与心肌肥厚及心力衰竭
摘要
心肌肥厚不仅是心脏对超负荷的一种功能性适应,而且是临床常见心血管疾病的并发症。长期持续性心肌肥厚最终导致心脏扩张、衰竭和猝死。循环超负荷是心肌肥大的最初作用因素,机械信号被心肌细胞感知,随之激活第二信使系统、MAPK途径和ERK途径,导致心肌细胞核基因的表达和蛋白合成。
出处
《世界核心医学期刊文摘（眼科学分册）》
2002年第1期23-25,共3页
Digest of the World Core Medical Journals:Ophthalmology
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