摘要
Purpose To evaluate whether an index based on hole configuration can be used t o predict visual outcome in eyes with idiopathic macular holes. Design Prospecti ve interventional case series. Methods Thirty five eyes of 32 patients with idi opathic stage 2 or 3 macular hole were enrolled in this study. The best correct ed visual acuity (BCVA), cross sectional image of the macular hole by optical c oherence tomography (OCT), and retinal thickness in the central ( < 1000 μm), i nner (1000 to 2220 μm), and outer ring areas (2220 to 3450 μm) as defined by t he OCT retinal mapping program were evaluated preoperatively and at 1, 3, 6, and 12 months postoperatively. The change in retinal thickness of the inner ring ar ea at the 6month postoperative period was used to evaluate the degree of preoper ative retinal deformation. The macular hole index (MHI) (ratio of hole height to base diameter of hole) was calculated and correlated with minimum diameter of h ole, base diameter of hole, the postoperative decrease in macular thickness, and the postoperative BCVA. The postoperative BCVA was further evaluated in two pat ient matched groups. Results Retinal thickness values in the inner ring area we re decreased at the 1 month postoperative period. MHI significantly correlated with the postoperative decrease in macular thickness in the inner ring area at 6 months (correlation coefficient=-0.632, P=.030, Spearman analysis) and with th e postoperative BCVA (P=.013, multiple regression analysis). Postoperative BCVA in the MHI ≥0.5 group was better than that in the MHI < 0.5 group (P= .032, Man n Whitney test). Conclusions The MHI is a ratio easily calculated from OCT tran sverse images of the macular area. The MHI represents the preoperative configura tion of a macular hole and is a prognostic factor for visual outcome.
Purpose To evaluate whether an index based on hole configuration can be used t o predict visual outcome in eyes with idiopathic macular holes. Design Prospecti ve interventional case series. Methods Thirty five eyes of 32 patients with idi opathic stage 2 or 3 macular hole were enrolled in this study. The best correct ed visual acuity (BCVA), cross sectional image of the macular hole by optical c oherence tomography (OCT), and retinal thickness in the central ( < 1000 μm), i nner (1000 to 2220 μm), and outer ring areas (2220 to 3450 μm) as defined by t he OCT retinal mapping program were evaluated preoperatively and at 1, 3, 6, and 12 months postoperatively. The change in retinal thickness of the inner ring ar ea at the 6month postoperative period was used to evaluate the degree of preoper ative retinal deformation. The macular hole index (MHI) (ratio of hole height to base diameter of hole) was calculated and correlated with minimum diameter of h ole, base diameter of hole, the postoperative decrease in macular thickness, and the postoperative BCVA. The postoperative BCVA was further evaluated in two pat ient matched groups. Results Retinal thickness values in the inner ring area we re decreased at the 1 month postoperative period. MHI significantly correlated with the postoperative decrease in macular thickness in the inner ring area at 6 months (correlation coefficient=-0.632, P=.030, Spearman analysis) and with th e postoperative BCVA (P=.013, multiple regression analysis). Postoperative BCVA in the MHI ≥0.5 group was better than that in the MHI < 0.5 group (P= .032, Man n Whitney test). Conclusions The MHI is a ratio easily calculated from OCT tran sverse images of the macular area. The MHI represents the preoperative configura tion of a macular hole and is a prognostic factor for visual outcome.
出处
《世界核心医学期刊文摘（眼科学分册）》
2005年第3期16-17,共2页
Digest of the World Core Medical Journals:Ophthalmology
