视神经萎缩和黄斑变性作为亚急性硬化性全脑炎的首发症状

Optic atrophy and macular degeneration as initial presentations of subacute sclerosing panencephalitis

To report a case of subacute sclerosing panencephalitis in which the initial c linical presentations were optic atrophy and macular degeneration. Observational case report. A 9 year old boy with visual loss attributable to optic atrophy and macular degeneration had a diagnostic examination. The visual acuity levels of both eyes were light perception at presentation. Fundus examination revealed bilateral optic atrophy and macular degenerative changes including retinal pigme nt epithelial atrophy, macular scarring, and epiretinal membrane formation. The antimeasles IgG titers were high both in serum and cerebrospinal fluid samples. Neurologic symptoms of myoclonus, ataxia, motor, and mental disabilities occurre d 4 months after the onset of first visual disturbances and 2 weeks after the pa tient applied to our clinic. Children with optic atrophy and macular degenerativ e lesions should be examined for sclerosing panencephalitis, even if the classic al neurologic symptoms of this disease are not present.