摘要
Background: High factor Ⅷ activity levels increase the risk of venous thromboembolism. This study was carried out to investigate the association between factor Ⅷ activity and central retinal vein occlusion (CRVO) in comparison to patients with a history of venous thrombosis and a healthy control group. Patients and Methods: We examined the factor Ⅷ activity in 62 patients with CRVO, 67 patients with venous thrombosis and 107 healthy individuals. The study measure employed for factor Ⅷ activity was a one- stage clotting assay. Results: 53.2% of the patients with CRVO had an elevated factor Ⅷ activity of more than 150% (>150 IU/dl). 78.5% of the patients with venous thrombosis and 19.7% of the healthy control group had an elevated factor Ⅷ activity ( > 150 IU/dl). Conclusions: Elevated factor Ⅷ activity is likely to have an influence on the pathogenesis of the central retinal vein occlusion.
Background: High factor Ⅷ activity levels increase the risk of venous thromboembolism. This study was carried out to investigate the association between factor Ⅷ activity and central retinal vein occlusion (CRVO) in comparison to patients with a history of venous thrombosis and a healthy control group. Patients and Methods: We examined the factor Ⅷ activity in 62 patients with CRVO, 67 patients with venous thrombosis and 107 healthy individuals. The study measure employed for factor Ⅷ activity was a one- stage clotting assay. Results: 53.2% of the patients with CRVO had an elevated factor Ⅷ activity of more than 150% (>150 IU/dl). 78.5% of the patients with venous thrombosis and 19.7% of the healthy control group had an elevated factor Ⅷ activity ( > 150 IU/dl). Conclusions: Elevated factor Ⅷ activity is likely to have an influence on the pathogenesis of the central retinal vein occlusion.
出处
《世界核心医学期刊文摘（眼科学分册）》
2005年第4期52-52,共1页
Digest of the World Core Medical Journals:Ophthalmology
