摘要
Background: The purpose of this study was to investigate the frequency of asym ptomatic left ventricular dysfunction in patients with pseudoexfoliation syndrom e. Methods: Two-dimensional and pulsed Doppler echocardiography of transmitral flow was performed on 27 patients with pseudoexfoliation syndrome, aged 66.9±5. 6 years, and 24 healthy volunteers aged 63.9±6.5 years. Left ventricular (LV) s ystolic contraction and ejection were assessed by LV ejection fraction (EF) and fractional shortening (FS). LV diastolic filling parameters tested were: early f ast diastolic filling (E wave), late diastolic filling (A wave), ratio E/A, velo city time integral E wave (VTIE) and A wave (VTIA), their ratio (VTIE/VTIA), pre ssure at the end of filling (LVEDP)-and a pulmonary capillary wedge pressure (P CWP). Results: Systolic parameters EF and FS, diastolic filling parameters such as A, LVEDP and PCWP were not significantly different between patients with pseu doexfoliation syndrome and controls (P > 0.05). A significant difference (P < 0. 05) was found with regard to the diastolic filling parameters: E (61.6±15.1 vs 83.7±21.4), ratio E/A (0.8±0.1 vs 1.1±0.2), VTIE (8.6±1.8 vs 9.8±1.9), VTIA (10.3±2.4 vs 7.8±1.6)-and ratio VTIA/VTIE (1.2±0.2 vs 0.8±0.2). Conclusion : Our study suggests the possibility of an association between patientswith pseu doexfoliation syndrome and a discrete asymptomatic myocardial diastolic dysfunct ion.
Background: The purpose of this study was to investigate the frequency of asym ptomatic left ventricular dysfunction in patients with pseudoexfoliation syndrom e. Methods: Two-dimensional and pulsed Doppler echocardiography of transmitral flow was performed on 27 patients with pseudoexfoliation syndrome, aged 66.9±5. 6 years, and 24 healthy volunteers aged 63.9±6.5 years. Left ventricular (LV) s ystolic contraction and ejection were assessed by LV ejection fraction (EF) and fractional shortening (FS). LV diastolic filling parameters tested were: early f ast diastolic filling (E wave), late diastolic filling (A wave), ratio E/A, velo city time integral E wave (VTIE) and A wave (VTIA), their ratio (VTIE/VTIA), pre ssure at the end of filling (LVEDP)-and a pulmonary capillary wedge pressure (P CWP). Results: Systolic parameters EF and FS, diastolic filling parameters such as A, LVEDP and PCWP were not significantly different between patients with pseu doexfoliation syndrome and controls (P > 0.05). A significant difference (P < 0. 05) was found with regard to the diastolic filling parameters: E (61.6±15.1 vs 83.7±21.4), ratio E/A (0.8±0.1 vs 1.1±0.2), VTIE (8.6±1.8 vs 9.8±1.9), VTIA (10.3±2.4 vs 7.8±1.6)-and ratio VTIA/VTIE (1.2±0.2 vs 0.8±0.2). Conclusion : Our study suggests the possibility of an association between patientswith pseu doexfoliation syndrome and a discrete asymptomatic myocardial diastolic dysfunct ion.
出处
《世界核心医学期刊文摘（眼科学分册）》
2005年第10期46-46,共1页
Digest of the World Core Medical Journals:Ophthalmology
