摘要
Background: Antibodies to a muscle-specific receptor tyrosine kinase (MuSK) h ave been found in approximately 40%of patients with generalized myasthenia grav is who are seronegative for the antiacetylcholine receptor antibody. Many of the patients with anti-MuSK antibodies have prominent oculobulbar symptoms or weak ness of the neck and respiratory muscles, but patients with ocular myasthenia ha ve not been described. Objective: To report a case of ocular myasthenia due to a nti-MuSK antibodies. Patient: A young woman with ocular myasthenia and antibodi es to MuSK. Results: Anti-MuSK antibody was detected by radioimmunoassay using highly purified MuSK recombinant antigen. Conclusion: Ocular myasthenia gravis i s a presentation of the anti-MuSK antibody syndrome.
Background: Antibodies to a muscle-specific receptor tyrosine kinase (MuSK) h ave been found in approximately 40%of patients with generalized myasthenia grav is who are seronegative for the antiacetylcholine receptor antibody. Many of the patients with anti-MuSK antibodies have prominent oculobulbar symptoms or weak ness of the neck and respiratory muscles, but patients with ocular myasthenia ha ve not been described. Objective: To report a case of ocular myasthenia due to a nti-MuSK antibodies. Patient: A young woman with ocular myasthenia and antibodi es to MuSK. Results: Anti-MuSK antibody was detected by radioimmunoassay using highly purified MuSK recombinant antigen. Conclusion: Ocular myasthenia gravis i s a presentation of the anti-MuSK antibody syndrome.
出处
《世界核心医学期刊文摘（眼科学分册）》
2005年第11期5-5,共1页
Digest of the World Core Medical Journals:Ophthalmology
