45岁以下男性的急性心肌梗死发生与纤溶蛋白、C-反应蛋白、纤维蛋白原、凝血因子Ⅶ、抗凝血酶、C蛋白和S蛋白、组织因子、血清D-二聚体、凝血酶原片段1+2的关系

Soluble fibrin, C-reactive protein, fibrinogen, factor VII, antithrombi n, proteins C and S, tissue factor, d-dimer, and prothrombin fragment 1+2 in men with acute myocardial infarction ≤45 years of age

To evaluate the contribution of hematologic factors and longterm inflammation to the development of myocardial infarction at a young age, we measured hematolo gic variables, including soluble fibrin and high-sensitivity C-reactive protei n, in 90 patients who had myocardial infarction and 138 controls ≤45 years of a ge. Plasma levels of soluble fibrin and C-reactive protein were significantly h igher in patients than in controls. On multivariate regression analysis, soluble fibrin was the strongest predictor of myocardial infarction at a young age.