摘要
针对33处病变,对西罗莫司洗脱支架(SES)近端和远端的5mm参照节段进行系列(基线时和随访9个月时)血管内超声分析。将近端和远端的参照节段分成长1mm的小段。
Serial (baseline and 9-month follow-up) intravascular ultrasound analysis was performed at 5-mm reference segments immediately proximal and distal to the sirolimus-eluting stent (SES) in 33 lesions. Proximal and distal reference segments were divided into 1-mm subsegments. Between postintervention and follow-up intravascular ultrasound studies, there were significant decreases in the lumen and increases in plaque &media areas in the subsegment closest to the distal edge, with no change in external elastic membrane area. There was no significant change in external elastic membrane, lumen, and plaque &media areas within the other subsegments. At the nearest 1-mm subsegment from the proximal and distal edges, baseline plaque &media area was associated with subsequent vessel remodeling. In conclusion, a large amount of plaque at the SES edge may be a risk of negative remodeling at follow-up (stent edge restenosis). It supports the importance of “normal-to-normal”SES deployment.
