期刊文献+

药物洗脱支架置入后再狭窄的类型:对西罗莫司和紫杉醇洗脱支架同期比较分析的认识

Patterns of restenosis after drug-eluting stent implantation: Insights from a contemporary and comparative analysis of sirolimus-and paclitaxel-eluting stents
下载PDF
导出
摘要 目的:评价在未经选择的可比性病变部位置入西罗莫司洗脱支架(SES)和紫杉醇洗脱支架(PES)后的再狭窄类型。方法和结果:对2003年3月至2005年3月间在本机构置入SES或PES后发生的所有再狭窄事件进行鉴定。 Aim: To evaluate patterns of restenosis following implantation of sirolimus-eluting stent (SES) and paclitaxel-eluting stent (PES) in comparable unselected lesions. Methods and results: We have identified all episodes of restenosis after SES or PES implantation in our institutions between March 2003 and March 2005. Restenosis pattern was classified as focal, diffuse, proliferative, or occlusive. The position of focal restenosis was also categorized as proximal, in-stent, distal, or multi-focal. We have characterized 150 and 149 restenotic lesions in SES and PES groups, respectively. The incidence of diffuse and occlusive restenosis was significantly higher in PES than in SES (47.6 vs. 27.0%, P < 0.001). Multivariable (OR 2.693, 95%CI 1.425-5.089, P=0.002) and propensity (OR 3.00, 95%CI 1.584-5.672, P < 0.001) analyses confirmed the positive association of PES with non-focal restenosis. For both stents, focal-edge restenosis was significantly more likely to occur proximally than distally (61.0 vs. 16.9%, P < 0.001 for PES and 45.8 vs. 16.8%, P < 0.001 for SES). Conclusion: Focal restenosis remains the most common pattern with SES. In contrast, just under half of restenosis in PES is the more severe non-focal pattern. Paradoxically, the majority of focal restenosis occurs at the proximal stent margin for both platforms.
  • 引文网络
  • 相关文献

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部