肝癌乙型肝炎病毒标志物模式与病毒载量的临床观察

Clinical observation of sign mode and quantity of B type hepatitis of liver cancer

目的:探讨原发性肝癌的发生与乙型肝炎标志物及乙肝病毒载量的关系。方法:对125例乙型病毒感染的原发性肝癌进行乙肝病毒标志物检测。其中31例检测了乙型肝炎病毒载量。结果:发现肝癌中乙肝病毒标志物HbsA g(+),HbeA b(+),HbcA b(+)模式59例(47.2%),占第一位。HbsA g(+),HbcA b(+)模式37例(29.6%),占第二位,它们分别与HbsA g(+),HbeA b(+),HbcA b(+)模式21例(16.8%)相比,有显著性差异。31例肝癌检测乙肝病毒载量在106cop ies/mL以下。结论:HbsA g(+),HbeA b(+),HbcA b(+)模式和HbsA g(+),HbcA b(+)模式是原发性肝癌的主要模式,原发性肝癌病毒载量不高。

Objective:To investigate the relationships between the sign mode and quantity of B type hepatitis and primary liver cancer.Methods:Sign mode of B type hepatitis were determined on 125 primary liver cancer patients who suffered from B type hepatitis,among which 31 cases received detection of the quantity of B type hepatitis.Results:Fifty-nine cases of HbsAg(+),HbeAb(+) and HbcAb(+) mode of B type hepatitis were found in liver cancer patients(47.2%),and 37 cases of HbsAg(+) and HbcAb(+) mode were the second most one(9.6%),which had significant differences with the mode of HbsAg(+),HbeAb(+) and HbcAb(+)(21 cases,16.8%).The quantity of B type hepatitis of 31 cases of liver cancer patients were below 106 copies/mL.Conclusion:Mode of HbsAg(+),HbeAb(+) and HbcAb(+) and mode of HbsAg(+) and HbcAb(+) were the main ones of primary liver cancer,and the quantity of B type hepatitis was not too much.