期刊文献+

胰岛素强化治疗对2型糖尿病患者胰岛β细胞功能的影响

下载PDF
导出
摘要 研究证明,胰岛β细胞功能受损在糖耐量异常阶段已经存在,以后β细胞的功能逐渐下降,糖耐量异常进一步发展为Ⅱ型糖尿病(T2DM),此时,胰岛β细胞的功能只有原来的50%,其后胰岛β细胞的功能逐渐衰竭至丧失[1]。为探讨胰岛β细胞的功能减低的T2DM患者短期胰岛素强化治疗后,空腹血糖、餐后血糖得到良好控制的同时,能否对胰岛β细胞的功能产生影响。
作者 于宏
出处 《临床医药实践》 2009年第6X期424-425,共2页 Proceeding of Clinical Medicine
  • 相关文献

参考文献2

二级参考文献6

  • 1American Diabetes Association. The pharmacological treatment of hyperglycemia in NIDDM. Diabetes Care, 1995,18 ( 11 ): 1510-1518.
  • 2Levy J, Atkinson AB, Bell PM, et al. Beta-cell deterioration determines the onset and rate of progression of secondary dietary failure in type 2 diabetes mellitus: the 10-year follow-up of the Belfast Diet Study. Diabet Med, 1998,15 (4) :290-296.
  • 3Haffner SM, Miettinen H, Stem MP. The homeostasis model in the San Antonio heart study. Diabetes Care, 1997,20(7) :1087-1092.
  • 4Sa JR, Silva RC, Nasri F,et al. Non-obese adult onset diabetes with oral hypoglycemic agent failure:islet cell auto antibodies or reversible beta cell refractoriness. Braz J Med Biol Res, 2003,36 ( 10 ):1301-1309.
  • 5Kosaka K, Kobayashi T,Nakanishi K, et al. Small doses of subcutaneous insulin as a strategy for preventing slowly progressive beta-cell failure in islet patients with clinical features of NIDDM. Diabetes,1996,45 ( 5 ) :622-626.
  • 6Rasmussen SB, Sorensen TS, Hansen JB, et al. Functional rest through intensive treatment with insulin and potassium channel openers preserves residual beta cell function and mass in acutely diabetic BB rats. Horm Metab Res,2000,32(7) :294-300.

共引文献63

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部