罗哌卡因与布比卡因在颈丛阻滞中应用

Ropivacaine and bupivacaine in the application of cervical plexus block

目的:观察比较0.35%、0.5%罗哌卡因、0.25%布比卡因在颈丛阻滞中的使用效果,总结三者特性及安全性,辩析三者效果的异同。方法:60例择期手术病人,随机分为0.35%罗哌卡因组(20例)、0.5%罗哌卡因组(20例)与0.25%布比卡因组(20例),观察三组起效时间、镇痛效果、镇痛持续时间及并发症反应。结果:三组药物起效时间差异无统计学意义,0.5%罗哌卡因相对0.25%罗哌卡因、0.25%布比卡因术后镇痛效果更佳。0.35%、0.5%罗哌卡因组的镇痛持续时间短于布比卡因组(P<0.05),循环系统并发症少于布比卡因组(P<0.05)。结论:二种浓度罗哌卡因用于颈丛阻滞与布比卡因相比镇痛效应相当,并发症少且恢复快,是安全、可行的,但0.5%罗哌卡因相对0.35%罗哌卡因术后镇痛效果更佳,且不增加其副作用。

Objective:Observation and comparison 0.35%,0.5% ropivacaine,0.25% bupivacaine in the cervical plexus block in the use of results,summing up the three characteristics and safety,Differentiation and Analysis of similarities and dif-ferences between the three effects.Methods:60 cases of elective surgery patients were randomly divided into 0.35% ropivacaine group(20 cases),0.5% ropivacaine group(20 cases) and 0.25% bupivacaine group(20 cases),observing the onset time of the three groups,analgesic effect,analgesic duration and complications of reaction.Results:The onset time of three groups of drugs was no significant difference,Ropivacaine 0.5% compared with 0.35% ropivacaine,bupivacaine for postoperative analgesia bet-ter effect.0.35%,0.5% ropivacaine group analgesic duration shorter than bupivacaine group(P<0.05),but the complications of circulatory system were fewer in the former group(P <0.05).Conclusion:Two kinds of concentrations of ropivacaine used for cervical plexus block with bupivacaine analgesic effect compared to equivalent,Fewer complications and quicker recovery,is safe,feasible,too.Ropivacaine 0.5% compared with 0.35% ropivacaine better postoperative analgesia without increasing side-effects.