纳洛酮与醒脑静注射液治疗肺性脑病的疗效观察

The efficacy of Naloxone and Xingnaojing Injection in pulmonary encephalopathy

目的:观察纳洛酮和醒脑静注射液治疗肺性脑病的疗效。方法:将入选的92例患者随机分为纳洛酮组、醒脑静组及对照组。对照组给予基础治疗,纳洛酮组在此基础上加用纳洛酮,醒脑静组在此基础上加用醒脑静。结果:纳洛酮组及醒脑静组有效率均显著高于对照组(P<0.01),纳洛酮组与醒脑静组疗效无统计学意义(P>0.05),治疗过程中除纳洛酮组有个别患者出现血压波动外,余无不良反应。结论:纳洛酮及醒脑静注射液治疗肺性脑病均优于传统的呼吸兴奋剂。

Objective:To evaluate the efficacy and safety of Naloxone and Xingnaojing Injection treatment for pulmonary encephalopathy.Methods:A total of 92 patients were randomly divided into naloxone group,Xingnaojing group and control group.The control group treated with basic therapy while naloxone group added naloxone,Xingnaojing group added Xingnaojing Injection.Results:Naloxone group and Xingnaojing group were significantly higher efficiency than control group(P<0.01).There were no significant difference between naloxone group and Xingnaojing group(P >0.05).Blood pressure uctuations were observed in individual patients,other patients with no adverse reactions.Conclusion:Naloxone and Xingnaojing Injection treatment of pulmonary encephalopathy were superior to the traditional respiratory stimulant.