泼尼松、环磷酰胺等联合黄芪注射液治疗过敏性紫癜肾炎的临床研究

Prednisone,cyclophosphamide and other Joint Injection Therapy HSP nephritis

目的:探讨泼尼松、环磷酰胺、阿司匹林联合黄芪注射液治疗过敏性紫癜肾炎的临床效果以及不良反应。方法:将118例过敏性紫癜肾炎患者随机分为A组与B组,两组均给予泼尼松和调节血脂等基础治疗,A组给予环磷酰胺、阿司匹林治疗,B组同时联合黄芪注射液治疗;疗程:均为16 w。结果:B组24 h尿蛋白定量、尿素氮、血肌酐、血脂、血浆白蛋白、血压、皮疹等指标的改善、泼尼松的用量和复发率等明显优于A组。结论:泼尼松、环磷酰胺、阿司匹林联合黄芪注射液治疗过敏性紫癜肾炎的效果明显好于泼尼松、环磷酰胺、阿司匹林等治疗的效果。

Objective:Of prednisone,cyclophosphamide,aspirin treatment of allergic purpura nephritis Astragalus clinical effects and adverse reactions.Methods:The 118 cases of allergic purpura nephritis were randomly divided into A group and B group,two groups were given prednisone and blood lipid treatment and other infrastructure,A group was given cyclophosphamide,aspirin therapy,B group also co-Astragalus Injection;course:all 16 weeks.Results:A group of 24h urinary protein,blood urea nitrogen,serum creatinine,blood lipids,serum albumin,blood pressure and other indicators of improvement,prednisone dosage and the relapse rate was better than B group.Conclusion:Prednisone,cyclophosphamide,aspirin Injection treatment of allergic purpura nephritis is better than prednisone,cyclophosphamide,aspirin and other treatment effects.