23例HIV感染者临床特点分析

The Clinical Characteristics Analysis of 23 HIV Positive Patients

目的探讨人类免疫缺陷病毒 (HIV)感染的临床特点和早期诊断。 方法用微粒酶免疫试验和蛋白印迹试验 ,对HIV感染者的血清进行HIV抗体初筛和确认 ,并对感染者的流行病学、机会性感染及免疫学、病毒学特点进行分析。 结果在 6 398份血清标本中 ,查出 2 3例HIV感染者 (3.6 0‰ ) ,上海户籍患者占 5 6 .5 % ;年龄以30 ～4 9岁为主。多经血、性和母婴等途径传播。早期症状常被忽略 ,以消化道、肺部霉菌、假单孢菌感染、巨细胞病毒感染、病毒性肝炎、皮损等就诊于各科室。多重或多部位的机会性感染可见于所有临床已发病患者。 结论多部位和 或多病原体感染是HIV感染的重要特征。

Objective To analyse the clinical characteristics of HIV infection and its early diagnosis. Methods HIV antibody was screened by the third era reagent ABBOTT(MEIA,S/O1.00),confirmed by Western Blot of Genelab company of USA and also confirmed by CDC shanghai.The characteristics of epidemiology,opportunistic infections,immunology and virology were also analyzed. Results Of 6 398 specimens of 23 were confirmed to be HIV positive,with a rate of 3.60‰.56.5% were Shanghai residents with age 30 ～ 49 years old mostly. Transmission was through blood,sex and mother-to-child.Early symptom of illness were often neglected .The presenting symptoms were those of multi-organs and/or multi-bacteria infections. Conclusion Multi-opportunistic infections is the important characteristic for HIV positive patients.