翼形轴流桨在红霉素发酵中的应用研究

Application of hydrofoil impeller to erythromycin fermentation

在20t工业发酵罐中,研究了翼形轴流桨搅拌对红霉素发酵过程的影响,重点考察了粘度、溶氧、效价等过程参数变化,以及搅拌功耗与发酵产量之间的关系。研究结果表明:(1)与传统的涡轮搅拌桨相比,翼形轴流桨搅拌其发酵过程参数(粘度、溶氧、效价等)随时间的变化曲线有明显的差异;(2)在相同的生产条件下,用翼形轴流桨代替涡轮桨可有效提高生产效率。

The effects of hydrofoil impeller on erythromycin fermentation and variation of fermentation parameter such as broth viscosity , dissolve oxygen , fermentation unit , power consumption on the scale of 20 ton fermentor, etc. with time were studied . The results showed that process parameters varied with time in fermentation was distinct for different agitator and the hydrofoil impeller instead of the disc turbine impeller might significantly reduce power consumption under the same condition.