子宫颈癌高剂量率^(60)Co和^(137)Cs腔内后装治疗的疗效分析

ANALYSIS OF RESULTS BETWEEN ^(60)CO AND ^(137)CS HDR AFTERLOADING IN THE TREATMENT OF CERVICAL CANCER

近来宫颈癌的放疗,国内多数学者主张采用高剂量率腔内后装治疗,常用的放射源为^(60)Co、^(137)Cs和^(192)Ir三种。我院妇科治疗室自1984年3月～1989年8月共收治宫颈癌576例,其中采用^(60)Co(Ralstron-20B)100例,^(137)Cs (Buchler)176例。本文重点分析子宫颈癌高剂量率后装治疗的疗效及其放疗反应,并对应用^(60)Co、和^(137)Cs放射源的疗效作一比较。

From.Mar 1984 to Aug 1989,576 patients were treated with high dose-rate intracavi-tary afterloading therapy in our hospital. These patients were divided into three groups:A. 400 patients with ^(60)Co, 50 Gy/5 wks to point A, B.100 patients with ^(137)Cs, 50Gy/5wks topoint A, C 76 patients with ^(137)Cs, 60 Gy/6 wks to point A. The dosage of external irra-diation was similar in the 3 groups 3-year survival rates of stage Ⅱ-Ⅲ cases treatedwith ^(60)Co and ^(137)Cs afterloading were 74. 2% (291/392) and 70. 7%(70/99) respectively,but the local uncontrolled rate was significantly higher in group B than those in groupsA and C. The incidence of late rectal and bladder reactions in both ^(60)Co and ^(137)Csgroups were nearly the same. The optimum dosage system was discussed.