摘要
本文报道用氮甲及氮甲为主联合化疗方案治疗36例多发性骨髓瘤。43程化疗的缓解率为49%,客观有效率68%,骨痛好转率达97%。1、3、5年生存率为89%、47%和33%。中位生存期35个月。副作用有胃肠反应和骨髓抑制。氮甲可作为治疗多发性骨髓瘤的首选药。
Thirty six patienis with multiple myeloma treated by combined chemotherapy containing N-formylsarcolysine (N-F) from 1960 to 1934 are reported. The response rate of entire group was 68%. The median remission time was 19 months. The 1, 3 and 5-year survival rates were 89% (32/36) 47% (17/36) and 33% (12/36) respectively. The median survival time was 35 months. The effect of N-F was simillar with melphalan. The regimens containing N-F were especially good in relearing skeletal pain. The side effects of the regimens were gastro-intestinal reaction and myelosuppression, but they were mild.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
1991年第2期99-101,共3页
Cancer Research on Prevention and Treatment