食管癌及胃癌在癌变过程中尿多胺含量变化的研究

THE LEVEL OF URINARY POLYAMINES IN THE HISTOCYTE-CANCERATION OF THE ESOPHAGUS AND STOMACH

本文报道采用尿多胺检测与胃镜活检普查相对照的方法,检测食管癌、胃癌高发区不同人群的尿多胺水平。证实尿多胺水平与食管或胃组织细胞的癌变程度有明显的平行关系。不典型增生时,尿多胺含量明显增加,升高80.33～115.15％,阳性率100％;癌变时升高160.62～213.75％,阳性率100％。表明尿多胺检测用以筛检潜在的、无症状的早期食管癌、胃癌病人和癌前期病人(不典型增生病例),是一项简便可行,灵敏可靠并为病人乐于接受的方法。

The article dwells on the detection of urinary polyamines in combihation with the gastroscopic general screening to detect the levels of urinary polyamines of varied polulation groups living in the high-incidence areas of esophageal cancer and gastrlc cancer. Findings confirmed that the Ievels of urinary polyamines were closely correlated with the extent of canceration of the histocytes of the esophagus and the stomach. 'When atypical proliferation developed, an apparent increase in such polyamines (80.33-115.15％ having a positlve rate of 100％) was detected. In cases of canceration, the elecation could be as high as 160.62-213.75％; positive rate: 100％. Such detection constitute a plain, possible, sensitive and reliable method that can easily be accepted by the patients with potential and symptomless esophageal cancer and gastric cancer of the early stage and by precancerous patients (cases of atypical proliferation).