慢性胃炎患者胃内24小时胆汁监测

Monitoring of bile reflux for patients with chronic gastritis

目的 胆汁反流是导致胃黏膜炎症的重要因素 ,该文研究不同类型慢性胃炎患者胃内胆汁反流情况。方法 分别对 45例慢性胃炎患者 (慢性浅表性胃炎 17例 ,慢性糜烂性胃炎 2 1例 ,慢性萎缩性胃炎 7例 )行胃内 2 4h胆汁监测 ,获得胆汁反流指标。分析胆汁反流总时间百分比、胆汁反流次数、胆汁反流 >5min次数和最长反流持续时间。结果 不同类型慢性胃炎组之间各项胆汁监测指标相差显著。胆汁反流总时间百分比在慢性萎缩性胃炎组 (16 .2± 18.0 )和慢性糜烂性胃炎组 (14.2± 12 .1)明显高于慢性浅表性胃炎组 (5 .3± 14.1,P <0 .0 1)。结论 胆汁反流与慢性糜烂性胃炎。

Objective To study the bile reflux in patients with different kind of chronic gastritis. Methods The changes of intragastric bile reflux during 24 h were assessed by using ambulatory bilirubin monitoring techniques in 45 patients(including 17 patients with chronic superficial gastritis, 21 with chronic erosive gastritis and 7 with chronic atrophic gastritis). Results The total time of intragastric bile reflux(%) was significantly greater in patients with chronic atrophic gastritis(16.2±18.0) and chronic erosive gastritis(14.2±12.1) than that in patients with chronic superficial gastritis(5.3±14.1, P<0.01). Conclusion Intragastric bile reflux is correlated with chronic erosive gastritis and atrophic gastritis.