硝酸甘油对冠心病伴青光眼患者眼内压的影响

Effect of nitroglycerin on intraocular pressure in patients with coronary heart disease and glaucoma

目的 :探讨硝酸甘油对冠心病伴青光眼患者眼压的影响。方法 :4 5例冠心病伴青光眼患者均以硝酸甘油舌下含化 ,观察其含药前 ,含药后 3、5、10、30min眼压变化。结果 :含药后 4次测眼压均较含药前均有所下降 ,且用药后 5、10min眼压下降明显 ,与治疗前比较 ,差异有显著性意义 (P <0 .0 5 )。结论

Objective:To study the effects of nitroglycerin on intraocular pressure in patients with coronary heart disease and glaucoma.Methods: Forty eight patients with coronary heart disease and glaucoma took nitroglycerin sublingually. Intraocular pressure was measured for five times, before and after 3, 5, 10, 30 minutes. Results: After taking nitroglycerin, intraocular pressure decreased in all patients, especially, in 5 minutes and 10 minutes (P< 0.05 ).Conclusion: For the patients with coronary heart disease and glaucoma, intraocular pressure does not increase after taking nitroglycerin.