摘要
目的 :探讨乙型肝炎病毒 (HBV)感染与非霍奇金淋巴瘤 (NHL)发病及临床特点的关系。方法 :应用 EL ISA法测定 NHL 患者确诊时的乙型肝炎病毒抗原抗体两对半。结果 :32例 NHL患者伴 HBV感染者 16例 (占 5 0 %) ,HBs Ag阳性者 6例 (占 18.8%) ,伴 HBV感染的 NHL 患者在化疗时肝功能异常发生率显著高于无 HBV感染的 NHL 患者。结论 :恶性淋巴瘤患者中 HBV感染远高于一般人群 ,HBV感染可能在 NHL 发病中起一定作用。伴 HBV感染的 NHL 患者在化疗时肝功能异常较常见 ,应予以充分的重视。
Objective:In order to study the pathogenesis and clinical features of non-Hodgkin′s lymphoma with hepatitis B virus infection.Methods:It is measured serum markers of HBV by ELISA technique in 32 NHL cases.Results:16 cases (50 %) had evidence of HBV infection,among which 5 cases (15.6 %) were positive for HBsAg.During chemotherapy,the frequence of liver dysfunction was higher in cases with HBV infection than that in cases without HBV infection.Conclusion:The prevalence of HBV infection was significantly higher in malignant lymphomas than general population,so it is possible that HBV infection play a role in the pathogenesis of NHL.Liver dysfuction was frequently occurred in cases of NHL patients with HBV infection during chemotherapy,we should pay attention to protecting liver fuction.
出处
《白血病.淋巴瘤》
CAS
2002年第4期202-204,共3页
Journal of Leukemia & Lymphoma
关键词
乙型肝炎病毒
非霍奇金淋巴瘤
感染
Hepatitis B virus infection
Non-Hodgkin′s lymphoma
Infection