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小剂量伊曲康唑防治造血干细胞移植早期真菌感染的临床观察 被引量:1

OBSERVATION OF CLINICAL EFFECT OF LOW DOSE ITRACONAZOLE IN PREVENTION AND TREATMENT FOR EARLY FUNGAL INFECTION AFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION
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摘要 目的 :探讨用小剂量伊曲康唑防治造血干细胞移植早期真菌感染的疗效。方法 :对1992年— 2 0 0 1年该院收治的 37例造血干细胞移植患者用小剂量伊曲康唑防治后早期真菌感染发生情况进行回顾性调查分析。结果 :真菌感染率为 8.1%,且感染程度轻 ,无真菌败血症发生 ,预后良好 ;伊曲康唑副作用少。结论 :口服小剂量伊曲康唑防治造血干细胞移植早期真菌感染疗效满意。 Objective:To evaluate the clinical effect of prevention and treatment of early fungal infection with low dose itraconazole after hematopoietic stem cell transplantation.Methods:The clinical effect of prevention and treatment of early fungal infection with low dose itraconazole was retrospectively studied in 37 patients undergoing hematopoietic stem cell transplantation from 1992 to 2001.Results:The incidence of fungal infection was 8.1 % in all 37 cases,of which had light degrees and good prognoses.No fungermia occurred.The side effect of itraconazole was fewer.Conclusion:The clinical effect of prevention and treatment of early fungal infection with low dose itraconazole after hematopoietic stem cell transplantation was satisfied.
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出处 《白血病.淋巴瘤》 CAS 2002年第4期209-211,共3页 Journal of Leukemia & Lymphoma
关键词 造血干细胞移植 真菌感染 伊曲康唑 预防 治疗 Hematopoietic stem cell transplantation Fungal infection Itraconazole Prevention Treatment
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